"You are holy and your name is holy, and holy ones praise you every day, forever. Blessed are you Hashem, the holy Lord."

Shebolei Haleketh records in the name of the Midrash: When Jacob our forefather was at the gateway to the heavens (on his way to Lavan), he sanctified there the name of Hashem. Immediately the angels in Heaven proclaimed, "Blessed are you Hashem, the holy Lord."

Consider! Surely the angels must have known before then that Hashem is holy. After all, the angels enjoy a constant proximity to the presence of Hashem. Unlike man, who only on rare occasions is able to feel that closeness with his creator, the angels constantly bask in His presence.

And yet, only now when the angels behold how Jacob, having seen in a dream vision the ladder reaching upward to the presence of Hashem, proceeded to sanctify Hashem's name--only then did the angels call out this blessing: "Blessed are you, Hashem, the holy Lord."

For in truth, it is man who must live in this world, who must find G-dliness within the ubiquity of the mundane. This is something which is not given even to the angels. Only man can aspire to achieve it.

When the angels saw that Jacob could lift himself above his dull and lowly surroundings and find even there the G-dly essence within, only then were they truly able to proclaim that throughout the entirety of the universe reverberates the recognition of the holiness of Hashem.

Rabbi Jacob Tzvi Mecklenberg, in his commentary on the prayers, explains the sequence of the blessings here at the beginning of the Shemoneh Esrei. In the second blessing, we speak of Hashem as the one who heals the sick, who releases the confined, who supports the fallen. Then in the next blessing we go on to say that important as all these are, there is a G-dliness in the world which transcends all of that, and through which we can aspire to lift ourselves above the ordinariness of our surroundings. That is the sanctity of the name of Hashem, and it is our job to bring it out and disseminate it in this world.